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Nuvigil vs. Provigil: Which Is Best for Narcolepsy?

Nuvigil vs. Provigil: Which Is Best for Narcolepsy?


Narcolepsy is a kind of problem where people feel overwhelming daytime drowsiness. The reason for the causes of narcolepsy is not well understood by the scientists. It also causes abnormal signalling in the brain. Treatment can lower the risk of narcolepsy. However, it cannot be cured properly. The best medicines to treat narcolepsy are Provigil and Nuvigil. 

They both are considered to be the best choice for narcolepsy. However, research states that Nuvigil lasts longer compared to Provigil. Both these medicines work differently and try to cure the problem. You should consult your physician and then you should take it. Other than that the medicines also possess some side effects. The common ones are headache, drowsiness, nausea, confusion, etc. The severe ones are rashes and allergic reactions, heartburn, sweat, etc. These two medicines share lots of similarities as well as differences. Both are FDA approved. Let’s find out which medicine is right for you. Follow the article and get a different type of information. 

Facts About Nuvigil And Provigil

Nuvigil lasts long compared to other medicines. It helps you to stay awake during the night time so that you can work peacefully. It is FDA-approved and treats several other problems excluding narcolepsy. Those are sleep apnea, shift work disorder, etc. It is considered to be one of the best medicines to treat narcolepsy and it lasts long. It is available in different doses like 50mg, 100mg, 200mg and 250mg. 

However, it should be only given when you need it. Without a doctor’s prescription, it is not advisable to take it. It might have some side effects. The common side effects are mentioned above. However, if you face severe side effects then you must contact your nearby physician. The doctor will guide you as per the dose. 

Next comes Provigil. It is another medicine to treat Narcolepsy. It is available in oral form and the doses are 100 and 200 mg. Those who have mild problems can use Provigil. It is because this medicine is a low dose. 

Whenever you are taking the medicine keep in mind to take light meals. Other than that, the medicine works fine if you take it in the early morning with snacks. If you are interested in taking Provigil then 150-250 mg medicine is perfect. On the other hand, Nuvigil will be effective if you take 200-400 mg. However, there is no proof that 400 mg medicine will work better compared to 200 mg medicine. 

Side Effects Of Nuvigil And Provigil

As mentioned earlier, any medicine has some kinds of side effects. Nuvigil and Provigil are no exceptions. The common side effects are headache, nausea, dizziness, nervousness, anxiety, mouth dryness, loss of appetite, facing trouble sleeping, etc. These are quite common. If you are facing this then there is nothing to worry about. However, in the case of some patients, the side effects become severe. 

The serious side effects of the medicines are as follows.

  • Dependency: Nuvigil and Provigil both are controlled substances. Hence, many people become dependent on it. It leads to misuse or overdose. If the medicines become an overdose then the patient can hallucinate and feel shortness of breath. Moreover, patients become highly dependent on it. Overdoses and dependency can become fatal. 
  • Skin rashes: After using these medicines many people faced skin problems. They also face severe rashes, itching and other problems. Research also states that skin problems like toxic epidermal necrolysis and Stevens-Johnson are very common problems of these two medicines. 
  • Allergic reactions: Another serious side effect is allergic reactions. It means swelling of lips and face. Reaction with Eosinophilia and System Symptoms syndrome (DRESS) is very common and many people suffer from it due to overdose. This is one of the life-threatening disease and causes serious rashes and problems. You should seek emergency help if you are suffering from any kind of allergic reaction. 
  • Mood swings: Mood swings are another major problem of the medicines if you are suffering from Narcolepsy. Mood swings like depression, suicidal thoughts and irritations will occur. Too much overdose of medicine will cause a psychiatric depression like bipolar disease. Bipolar disease is incurable and it can lead to severe depression. Hence you need to consult the doctor as soon as possible. Your doctor will decide whether to continue the medicines or not. 
  • Heart problems: The patient also suffers from cardiovascular problems. If you are already a patient of heart disease then you must not take it. Staying away from these medicines will be helpful if you have any heart problems. You need to make sure that your healthcare provider knows all the details of your medical history or not. 

Are Nuvigil And Provigil Effective? 

Yes, both Nuvigil and Provigil are highly effective medicines to treat the problem of Narcolepsy. Though these are composed of different chemical compositions. The medicines are given to the patients after a detailed study of them. 

Physicians study patients ‘ histories from the very beginning. After realizing all the pros and cons then only they prescribed the dose and medicine to the patients. However, according to research, it is concluded that Nuvigil lasts longer in the body. It means one tablet is enough for you to stay awake during the daytime. On the other hand, Provigil takes time to start to function. Both are good and chemically different. Depending upon the side effects you can choose the medicine and start taking it. 

Before you buy Provigil online you should look at the expiry date and other compositions. 


Lastly, it is important for us to state that Provigil 200mg and Nuvigil 400 will function the same despite the different composition of the medicines. You can try any one of these medicines for the side effects. Severe side effects will make your physician stop taking it. It is always advisable to consult your doctor and take the medicine. Many patients take the medicine of their own and suffer later on. The effect of narcolepsy can only be curable if you take the medicines on time. 


Smith is a professional content writer and blogger, who specializes in product pages, ghost blogging, and marketing campaigns, also helping the marketing team to understand numerous content marketing strategies. Cooper has conducted various writing craft workshops for professional writers groups and book conferences, and also offers online fiction writing courses.